RUN’s feedback is primarily focussed upon the research infrastructure and research-trained workforces available to the economies, industries and communities of regional Australia. Since its inception in 2006, successive NRI Roadmaps have done little to address the accelerating concentration of Australia’s national research infrastructure and research-trained workforces gravitating towards the largest capital cities. Despite the appetite for enhanced, place-based innovative research capabilities within Australia’s regions, and the incredible talent and world class universities that the regions host, this trend continues at pace. The disproportionately diminished dividends flowing to regional Australia from the national RD&I system remains one of RUN’s foremost concerns.